AustralieFrV1, Main, Exploration, bibRecord, 006C35

Consensus for Managing Acute Severe U Icerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN

Identifieur interne : 006C35 ( Main/Exploration ); précédent : 006C34; suivant : 006C36

Consensus for Managing Acute Severe U Icerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN

Auteurs : Dan Turner [Israël] ; Simon P. L. Travis [Royaume-Uni] ; Anne M. Griffiths [Canada] ; Frank M. Ruemmele [France] ; Arie Levine [Israël] ; Eric I. Benchimol [Canada] ; Marla Dubinsky [États-Unis] ; George Alex [Australie] ; Robert N. Baldassano [États-Unis] ; Jacob C. Langer [Canada] ; Robert Shamberger [États-Unis] ; Jeffrey S. Hyams [États-Unis] ; Salvatore Cucchiara [Italie] ; Athos Bousvaros [États-Unis] ; Johanna C. Escher [Pays-Bas] ; James Markowitz [États-Unis] ; David C. Wilson [Royaume-Uni] ; Gert Van Assche [Belgique] ; Richard K. Russell [Royaume-Uni]

Source :

The American journal of gastroenterology [ 0002-9270 ] ; 2011.

RBID : Pascal:11-0206849

Descripteurs français

Pascal (Inist)
- Rectocolite ulcérohémorragique, Entérite de Crohn, Aigu, Colite, Enfant, Article synthèse, Revue bibliographique, Articulation, Gastroentérologie.
Wicri :
- topic : Enfant.

English descriptors

KwdEn :
- Acute, Bibliographic review, Child, Colitis, Crohn disease, Gastroenterology, Joint, Review, Ulcerative colitis.

Abstract

OBJECTIVES: Acute severe ulcerative colitis (ASC) is a potentially life-threatening disease. We aimed to formulate guidelines for managing ASC in children based on systematic review of the literature and robust consensus process. This manuscript is a product of a joint effort of the ECCO (European Crohn's and Colitis Organization), the Pediatric Porto Inflammatory Bowel Disease (IBD) Working group of ESPGHAN (European Society of Pediatric Gastroenterology, Hepatology, and Nutrition) and ESPGHAN. METHODS: A group of 19 experts in pediatric IBD participated in an iterative consensus process including two face-to-face meetings. A total of 17 predefined questions were addressed by working subgroups based on a systematic review of the literature. RESULTS: The recommendations and practice points were eventually endorsed with a consensus rate of at least 95% regarding: definitions, initial evaluation, standard therapy, timing of second-line therapy, the role of endoscopic evaluation and heparin prophylaxis, how to administer second-line medical therapy, how to assess response, surgical considerations, and discharge recommendations. A management flowchart is presented based on daily scoring of the Pediatric Ulcerative Colitis Activity Index (PUCAI), along with 28 formal recommendations and 34 practice points. CONCLUSIONS: These guidelines provide clinically useful points to guide the management of ASC in children. Taken together, the recommendations offer a standardized protocol that allows effective monitoring of disease progress and timely treatment escalation when needed.

Affiliations:

Australie, Belgique, Canada, France, Israël, Italie, Pays-Bas, Royaume-Uni, États-Unis
Angleterre, Californie, Connecticut, Hollande-Méridionale, Latium, Massachusetts, Ontario, Oxfordshire, Pennsylvanie, Écosse, État de New York, Île-de-France
Oxford, Paris, Rome, Rotterdam, Toronto, Édimbourg
Université Paris-Descartes, Université d'Édimbourg, Université de Toronto

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 001E18
to stream PascalFrancis, to step Curation: 004122
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Le document en format XML

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<author><name sortKey="Cucchiara, Salvatore" sort="Cucchiara, Salvatore" uniqKey="Cucchiara S" first="Salvatore" last="Cucchiara">Salvatore Cucchiara</name>
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<author><name sortKey="Escher, Johanna C" sort="Escher, Johanna C" uniqKey="Escher J" first="Johanna C." last="Escher">Johanna C. Escher</name>
<affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Department of Pediatric Gastroenterology, ErasmusMC-Sophia Children's Hospital</s1>
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<author><name sortKey="Markowitz, James" sort="Markowitz, James" uniqKey="Markowitz J" first="James" last="Markowitz">James Markowitz</name>
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<author><name sortKey="Van Assche, Gert" sort="Van Assche, Gert" uniqKey="Van Assche G" first="Gert" last="Van Assche">Gert Van Assche</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Consensus for Managing Acute Severe U Icerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN</title>
<author><name sortKey="Turner, Dan" sort="Turner, Dan" uniqKey="Turner D" first="Dan" last="Turner">Dan Turner</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem</s1>
<s2>Jerusalem</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Jerusalem</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Travis, Simon P L" sort="Travis, Simon P L" uniqKey="Travis S" first="Simon P. L." last="Travis">Simon P. L. Travis</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Translational Gastroenterology Unit, John Radcliffe Hospital</s1>
<s2>Oxford</s2>
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<sZ>2 aut.</sZ>
</inist:fA14>
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<author><name sortKey="Griffiths, Anne M" sort="Griffiths, Anne M" uniqKey="Griffiths A" first="Anne M." last="Griffiths">Anne M. Griffiths</name>
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<author><name sortKey="Dubinsky, Marla" sort="Dubinsky, Marla" uniqKey="Dubinsky M" first="Marla" last="Dubinsky">Marla Dubinsky</name>
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<author><name sortKey="Alex, George" sort="Alex, George" uniqKey="Alex G" first="George" last="Alex">George Alex</name>
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<author><name sortKey="Baldassano, Robert N" sort="Baldassano, Robert N" uniqKey="Baldassano R" first="Robert N." last="Baldassano">Robert N. Baldassano</name>
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<affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto</s1>
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<country>Canada</country>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
<orgName type="university">Université de Toronto</orgName>
</affiliation>
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<author><name sortKey="Shamberger, Robert" sort="Shamberger, Robert" uniqKey="Shamberger R" first="Robert" last="Shamberger">Robert Shamberger</name>
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<s2>Boston, Massachusetts</s2>
<s3>USA</s3>
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</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
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<author><name sortKey="Hyams, Jeffrey S" sort="Hyams, Jeffrey S" uniqKey="Hyams J" first="Jeffrey S." last="Hyams">Jeffrey S. Hyams</name>
<affiliation wicri:level="2"><inist:fA14 i1="11"><s1>Connecticut Children's Medical Center, Hartford, University of Connecticut School of Medicine</s1>
<s2>Farmington, Connecticut</s2>
<s3>USA</s3>
<sZ>12 aut.</sZ>
<sZ>14 aut.</sZ>
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<placeName><region type="state">Connecticut</region>
</placeName>
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<author><name sortKey="Cucchiara, Salvatore" sort="Cucchiara, Salvatore" uniqKey="Cucchiara S" first="Salvatore" last="Cucchiara">Salvatore Cucchiara</name>
<affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Sapienza University of Rome</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bousvaros, Athos" sort="Bousvaros, Athos" uniqKey="Bousvaros A" first="Athos" last="Bousvaros">Athos Bousvaros</name>
<affiliation wicri:level="2"><inist:fA14 i1="11"><s1>Connecticut Children's Medical Center, Hartford, University of Connecticut School of Medicine</s1>
<s2>Farmington, Connecticut</s2>
<s3>USA</s3>
<sZ>12 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Escher, Johanna C" sort="Escher, Johanna C" uniqKey="Escher J" first="Johanna C." last="Escher">Johanna C. Escher</name>
<affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Department of Pediatric Gastroenterology, ErasmusMC-Sophia Children's Hospital</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Markowitz, James" sort="Markowitz, James" uniqKey="Markowitz J" first="James" last="Markowitz">James Markowitz</name>
<affiliation wicri:level="2"><inist:fA14 i1="14"><s1>Division of Pediatric Gastroenterology, Steven and Alexandra Cohen Children's Medical Center of New York, North Shore-LIJ Health System</s1>
<s2>New Hyde Park, New York</s2>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilson, David C" sort="Wilson, David C" uniqKey="Wilson D" first="David C." last="Wilson">David C. Wilson</name>
<affiliation wicri:level="4"><inist:fA14 i1="15"><s1>Child Life and Health, University of Edinburgh</s1>
<s2>Edinburgh Scotland</s2>
<s3>GBR</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Van Assche, Gert" sort="Van Assche, Gert" uniqKey="Van Assche G" first="Gert" last="Van Assche">Gert Van Assche</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Division of Gastroenterology, University Hospital Leuven</s1>
<s2>Leuven</s2>
<s3>BEL</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Belgique</country>
<wicri:noRegion>Leuven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Russell, Richard K" sort="Russell, Richard K" uniqKey="Russell R" first="Richard K." last="Russell">Richard K. Russell</name>
<affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Royal Hospital for Sick Children</s1>
<s2>Glasgow, Scotland</s2>
<s3>GBR</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Royal Hospital for Sick Children</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The American journal of gastroenterology</title>
<title level="j" type="abbreviated">Am. j. gastroenterol.</title>
<idno type="ISSN">0002-9270</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The American journal of gastroenterology</title>
<title level="j" type="abbreviated">Am. j. gastroenterol.</title>
<idno type="ISSN">0002-9270</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute</term>
<term>Bibliographic review</term>
<term>Child</term>
<term>Colitis</term>
<term>Crohn disease</term>
<term>Gastroenterology</term>
<term>Joint</term>
<term>Review</term>
<term>Ulcerative colitis</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Rectocolite ulcérohémorragique</term>
<term>Entérite de Crohn</term>
<term>Aigu</term>
<term>Colite</term>
<term>Enfant</term>
<term>Article synthèse</term>
<term>Revue bibliographique</term>
<term>Articulation</term>
<term>Gastroentérologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Enfant</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">OBJECTIVES: Acute severe ulcerative colitis (ASC) is a potentially life-threatening disease. We aimed to formulate guidelines for managing ASC in children based on systematic review of the literature and robust consensus process. This manuscript is a product of a joint effort of the ECCO (European Crohn's and Colitis Organization), the Pediatric Porto Inflammatory Bowel Disease (IBD) Working group of ESPGHAN (European Society of Pediatric Gastroenterology, Hepatology, and Nutrition) and ESPGHAN. METHODS: A group of 19 experts in pediatric IBD participated in an iterative consensus process including two face-to-face meetings. A total of 17 predefined questions were addressed by working subgroups based on a systematic review of the literature. RESULTS: The recommendations and practice points were eventually endorsed with a consensus rate of at least 95% regarding: definitions, initial evaluation, standard therapy, timing of second-line therapy, the role of endoscopic evaluation and heparin prophylaxis, how to administer second-line medical therapy, how to assess response, surgical considerations, and discharge recommendations. A management flowchart is presented based on daily scoring of the Pediatric Ulcerative Colitis Activity Index (PUCAI), along with 28 formal recommendations and 34 practice points. CONCLUSIONS: These guidelines provide clinically useful points to guide the management of ASC in children. Taken together, the recommendations offer a standardized protocol that allows effective monitoring of disease progress and timely treatment escalation when needed.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Belgique</li>
<li>Canada</li>
<li>France</li>
<li>Israël</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Californie</li>
<li>Connecticut</li>
<li>Hollande-Méridionale</li>
<li>Latium</li>
<li>Massachusetts</li>
<li>Ontario</li>
<li>Oxfordshire</li>
<li>Pennsylvanie</li>
<li>Écosse</li>
<li>État de New York</li>
<li>Île-de-France</li>
</region>
<settlement><li>Oxford</li>
<li>Paris</li>
<li>Rome</li>
<li>Rotterdam</li>
<li>Toronto</li>
<li>Édimbourg</li>
</settlement>
<orgName><li>Université Paris-Descartes</li>
<li>Université d'Édimbourg</li>
<li>Université de Toronto</li>
</orgName>
</list>
<tree><country name="Israël"><noRegion><name sortKey="Turner, Dan" sort="Turner, Dan" uniqKey="Turner D" first="Dan" last="Turner">Dan Turner</name>
</noRegion>
<name sortKey="Levine, Arie" sort="Levine, Arie" uniqKey="Levine A" first="Arie" last="Levine">Arie Levine</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Travis, Simon P L" sort="Travis, Simon P L" uniqKey="Travis S" first="Simon P. L." last="Travis">Simon P. L. Travis</name>
</region>
<name sortKey="Russell, Richard K" sort="Russell, Richard K" uniqKey="Russell R" first="Richard K." last="Russell">Richard K. Russell</name>
<name sortKey="Wilson, David C" sort="Wilson, David C" uniqKey="Wilson D" first="David C." last="Wilson">David C. Wilson</name>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Griffiths, Anne M" sort="Griffiths, Anne M" uniqKey="Griffiths A" first="Anne M." last="Griffiths">Anne M. Griffiths</name>
</region>
<name sortKey="Benchimol, Eric I" sort="Benchimol, Eric I" uniqKey="Benchimol E" first="Eric I." last="Benchimol">Eric I. Benchimol</name>
<name sortKey="Langer, Jacob C" sort="Langer, Jacob C" uniqKey="Langer J" first="Jacob C." last="Langer">Jacob C. Langer</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Ruemmele, Frank M" sort="Ruemmele, Frank M" uniqKey="Ruemmele F" first="Frank M." last="Ruemmele">Frank M. Ruemmele</name>
</region>
</country>
<country name="États-Unis"><region name="Californie"><name sortKey="Dubinsky, Marla" sort="Dubinsky, Marla" uniqKey="Dubinsky M" first="Marla" last="Dubinsky">Marla Dubinsky</name>
</region>
<name sortKey="Baldassano, Robert N" sort="Baldassano, Robert N" uniqKey="Baldassano R" first="Robert N." last="Baldassano">Robert N. Baldassano</name>
<name sortKey="Bousvaros, Athos" sort="Bousvaros, Athos" uniqKey="Bousvaros A" first="Athos" last="Bousvaros">Athos Bousvaros</name>
<name sortKey="Hyams, Jeffrey S" sort="Hyams, Jeffrey S" uniqKey="Hyams J" first="Jeffrey S." last="Hyams">Jeffrey S. Hyams</name>
<name sortKey="Markowitz, James" sort="Markowitz, James" uniqKey="Markowitz J" first="James" last="Markowitz">James Markowitz</name>
<name sortKey="Shamberger, Robert" sort="Shamberger, Robert" uniqKey="Shamberger R" first="Robert" last="Shamberger">Robert Shamberger</name>
</country>
<country name="Australie"><noRegion><name sortKey="Alex, George" sort="Alex, George" uniqKey="Alex G" first="George" last="Alex">George Alex</name>
</noRegion>
</country>
<country name="Italie"><region name="Latium"><name sortKey="Cucchiara, Salvatore" sort="Cucchiara, Salvatore" uniqKey="Cucchiara S" first="Salvatore" last="Cucchiara">Salvatore Cucchiara</name>
</region>
</country>
<country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Escher, Johanna C" sort="Escher, Johanna C" uniqKey="Escher J" first="Johanna C." last="Escher">Johanna C. Escher</name>
</region>
</country>
<country name="Belgique"><noRegion><name sortKey="Van Assche, Gert" sort="Van Assche, Gert" uniqKey="Van Assche G" first="Gert" last="Van Assche">Gert Van Assche</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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Consensus for Managing Acute Severe U Icerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN

Consensus for Managing Acute Severe U Icerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN

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